Pharmacological properties of donepezil hydrochloride (Aricept), a drug for Alzheimer's disease.

Comparison of the Effects of a Brand-name Drug and Its Generic Drug on the Quality of Life of Alzheimer’s Disease Patients

OBJECTIVE The pharmacological effects of generic (GE) donepezil are the same as Aricept, its brand-name counterpart. However, little is known as to whether these two drugs provide the same quality of life (QOL). The study subjects were patients with Alzheimer's disease who were taking donepezil hydrochloride tablets, and were selected by visiting either the local pharmacies or the patients' hom...

Drug treatments for Alzheimer's disease: Aricept, Exelon, Reminyl and Ebixa

The action of Ebixa is quite different to, and more complex than, that of Aricept, Exelon and Reminyl. Ebixa blocks a messenger chemical, known as a neurotransmitter glutamate. Glutamate is released in excessive amounts when brain cells are damaged by Alzheimer's disease, which causes the brain cells to be damaged further. Ebixa can protect brain cells by blocking this release of excess glutamate.

Acrescent, INN- memantine hydrochloride / donepezil hydrochloride

Impaired attention in the 3xTgAD mouse model of Alzheimer's disease: rescue by donepezil (Aricept).

Several mouse models of Alzheimer's disease (AD) with abundant β-amyloid and/or aberrantly phosphorylated tau develop memory impairments. However, multiple non-mnemonic cognitive domains such as attention and executive control are also compromised early in AD individuals. Currently, it is unclear whether mutations in the β-amyloid precursor protein (APP) and tau are sufficient to cause similar,...

Effect of Donepezil Hydrochloride on Cognitive Function

Objective: To explore the effect of donepezil hydrochloride on the cognitive function recovery of the rats with Alzheimer’s disease and the positive expression of nitric oxide synthase and acetylcholinesterase (NOS and AchE) in brain tissues of rats with Alzheimer's disease (AD). Methods: Forty SD (Sprague Dawley) rats were randomly classified into model group, treatment group, control group an...